Automated function prediction in protein structures

WebFEATURE  
Scan a structure for function
(For assistance, please see our detailed instructions)

Step 1: Choose a structure
Structure: PDB ID or Upload (PDB format)

Step 2: Choose a type of site to scan for
(NOTE: Choosing "All_SeqFEATURE_models" may take longer to scan. If you have a large protein, you should choose "Email" runmode in Step 3 to have your results emailed to you.)

Model:

Step 3: Choose run mode
Run mode: Interactive Email:

Step 4: Submit and view results


WebFEATURE uses Jmol which requires Java 1.5.0 for visualization of results. These pages require Java and Javascript for proper interactivity. Visualization and interactivity can also be performed off-line using software packages such as RasMol, PyMol, and Chimera.


EXAMPLES:
ModelPDBIDDescriptionRuntime
Calcium binding site3icbIntestinal Calcium Binding Protein5 secs
ATP binding site1csnCasein Kinase-145 secs
Chloride binding site1pmlTissue Plasminogen Activator Kringle 225 secs
Diffuse bound Mg for RNA1ajfP5B Stem-Loop from Group I Intron5 secs
Site bound Mg for RNA1gidP4-P6 RNA Ribozyme Domain from Group I Intron60 secs
Trypsin model (SeqFeature)1bqyPlasminogen Activator (Tsv-Pa) From Snake Venom5 secs

Principal investigator: Russ Altman